Should be straight forward using Grid or divs to wrap the Collection Lists.
Create a Collection List to display just the big featured blog by creating a filter to show just the featured blog. Then place the single collection list in your desired area,
Then create a Collection List for the 4 blogs to the right of featured. Filter by displaying blogs 2-5.
Using Grid or a 50% width div will make things easier when you want to adjust the layout for mobile devices.
All other blogs can appear underneath in the usual way using the Collection List