On mobile and tablet if you have a lightbox image in your site and you happen to touch it will scrolling down the site it will activate the lightbox when the page finished scrolling. This isn't so much an issue if you only have a couple lightboxes on a page but if you have a page with a lot of the thumbnails the likelihood of touching one while scrolling the page is much higher. And on Mobile the lightbox images are much larger so they're even harder to avoid while scrolling.
I'm still getting a lot of strange behavior on Mobile Landscape. Doesn't happen all the time but it's not hard to get it to happen (See Images) Also, when it starts doing this you can't close the lightbox without having to reload the page.